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Augusta, ME
A 40-year-old female asked about a female:

Positive ana titer 1:80 homogenous in my 10 year old daughter. chronic fatigue and repeat kidney infections. could it be pediatric systemic lupus?

4 doctor answers5 doctors weighed in
Dr. Gloria Lopez
Pediatrics 46 years experience
It could: ANA (antinuclear antibodies) are a group of auto-antibodies produced by a person's immune system when it fails to adequately distinguish between "self" and "nonself" and cause organ and tissue damage. It’s most often used as one of the tests to help diagnose systemic lupus erythematosus (SLE). 97 % of patients with lupus will have a positive antinuclear antibody test (ANA).
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Dr. Jane Eason
35 years experience
ANA: The ANA, antinuclear antibody, is a nonspecific test that might suggest a connective tissue disorder, but might not. I'm wondering why the test was sent. In any case, given the result, it would be reasonable for your provider to either send off a more complete panel of tests, or refer your daughter to a Rheumatologist.
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Dr. Nela Cordero
Pediatrics 56 years experience
LUPUS: Lupus test has to become positive for DX.ANA is also positive in other collagen diseases .
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Christine Hom
Pediatrics 32 years experience
Unlikely: Kidney infections are not typical for lupus. Patients with lupus can have fatigue, but they also have very specific findings like anemia, arthritis, rash, mouth sores, protein in the urine.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Nov 28, 2017

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