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A 28-year-old female asked:

I have recurring flares of rashes, joint pain, muscle aches, debilitating fatigue, dizziness. i have photosensitity and one episode of my wbc at 2.0 years back. my ana is 6:40. i'm on plaquenil. why are all my other antibodies neg for lupus?

3 doctor answers5 doctors weighed in
Dr. Nela Cordero
Pediatrics 56 years experience
LUPUS: Are you under the care of a rheumatologist? They know what they are doing and will even tell you what kind of lupus you have, discoid or systemic? Pls ask your md.
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Dr. Ed Friedlander
Pathology 46 years experience
ANA 1:640?: Concerning for lupus as is everything else you tell me, though the language is somewhat vague. Consider a visit with a second rheumatologist with whom you may have better rapport. Key to rheumatologic disease is the trusting relationship between physician and patient; perhaps the two of you simply did not hit it off, as has happened to me from time to time. Lupus is brutal, you deserve the best.
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Dr. Dan Fisher
Internal Medicine 29 years experience
Maybe SLE maybe not.: Diagnosis of rheumatologic disease is generally based on symptoms with support from lab. Sounds like you have a rheumatologic disease and are being treated with a rheumatologic agent perhaps by a rheumatologist. They can explain your particular situation better, but suffice it to say tests are not always right and a single test does not generally make or break a diagnosis.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Nov 21, 2020

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