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A member asked:
Currently being tx'd for psa with plaquenil and stelera. last 2 years i've had 1 positive ana but my (ds) dna runs extremely high between 835 - 2200 iu/ml. i suffer from extreme fatigue and joint and body aches. lupus? another autoimmune disease?
A doctor has provided 1 answer
dsDNA is quite specific for SLE, not for PSA. I will be surprised if you were not diagnosed with SLE with that dsDNA titer. If you have any doubt, positive Smith antibody should confirm the diagnosis with your current symptoms.
Answered 1/24/2022
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