A 38-year-old female asked:
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38 year old female fatigued, bloating, gas.hx of fluctuating liver enzymes for almost 3 years. gallbladder removed 1.5 years ago. alt 61, alkaline phosphatase 154, globulin 3.9.hep, ana, lupus, rheumatoid all negative.please help.other suggestions?

2 doctor answers
Dr. Emran Rouf
Specializes in Internal Medicine
Possible celiac : Celiac disease remains a possibility with reported symptoms and liver function test abnormalities. An evaluation with a liver specialist may be needed for reviewing additional history and consideration for tests to rule out disorders of biliary tree, pancreas, and chronic liver diseases.
Answered on Mar 22, 2020
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Dr. Anca Sisu
Dr. Anca Sisu commented
18 years experience Family Medicine
Consider fatty liver, check for metabolic syndrome
Mar 14, 2017
Dr. Alvin Wells
41 years experience Rheumatology
GI issues: The good news is it does not appear that you have an autoimmune or an inflammatory process. The symptoms may be suggestive of irritable bowel syndrome vs. chronic fatigue vs. other. I would recommend screening for viruses that may be associated such as EBV, etc. The best course would be careful monitoring for clinical and lab changes. I would be happy to consult if needed.
Answered on Mar 16, 2017

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