A member asked:

Is taking st john's wort with wellbutrin safe? psych told me to raise serotonin i don't feel comfortable taking serotonin meds. please don't refer me me back to prescriber if you can't answer, thank you?

2 doctors weighed in across 2 answers
Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

There is no interaction between st john's wort and wellbutrin.

Answered 11/30/2021

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See no rationale to add St John's Wort to Wellbutrin, as this would be a redundant and likely ineffectual combination at best. Better to adjust dose of Wellbutrin. Also, attempting to raise serotonin could result in "Serotonin Syndrome".

Answered 11/30/2021

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