Not common: It is not uncommon to combine meds such as zoloft and wellbutrin. They work different ways s Zoloft increases serotonin, and wellbutrin results in increased norepinepherine and dopamine . IF one only gets a partial response on zoloft sometimes adding wellbutrin improves the response . Taking over 450mg of wellbutrin can result in seizures, serotonin syndrome unlikely
Answered 7/23/2019
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