A member asked:

Concerning prozone do antibody levels change could you have a high level causing a false neg. rpr then they drop 2nd test n get + test?

A doctor has provided 1 answer

Dr. Gurmukh Singh answered

Possible: Antibody levels do change. They start out low, increase and could reach levels to cause prozone phenomenon and then drop with time. If prozone is a concern, your laboratory can make dilutions of the sample to address this issue. You may wish to talk to the pathologist in-charge of the lab that did the tests.

Answered 5/20/2019

175 views

Thank

More of what we treat

Allergies

Antibiotics

Asthma

High Blood Pressure

Prescriptions

Type 2 Diabetes

Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.

Get Virtual Care

For Businesses

About Us

HealthTap Online Primary Care Doctors Accepting New Patients

A member asked:

Concerning prozone do antibody levels change could you have a high level causing a false neg. rpr then they drop 2nd test n get + test?

A doctor has provided 1 answer

Dr. Gurmukh Singh answered

Related Questions

A member asked:

Dr Syphilis question exposure April 1 tested RPR neg at june 2, 54 days but was on z pak a day before then due to antibiotics thought to test again, RPR test again aug 2 120 days its conclusive? Thanks?

A member asked:

Confusing for me, syphilis, not here to Frustrate Drs last talk as i mentioned test neg at 8 weeks RPR while on z pak a day before and then waited i make sure didnt take any antibiotics then test again at 16 wek neg RPR no need for additional test?

A member asked:

What are the chances of a Syphilis RPR test result changing from negative at 9 weeks to positive after the 12 week mark? Do the 3 weeks make much difference in regards to antibody production?

A member asked:

A little cloudy on my test: What a does a syphilis RPR (DX) W/REFL TITER AND CONFIRMATORY TESTING measure? They also gave me an antibody test at 14 weeks. Both tests were negative. Does it rule out syphilis at 14 weeks? Conclusive?

A member asked:

Will antinuclear antibody test detect dormant syphilis? I am waiting on results and had a RPR test came back was non reactive.

Sponsored Content

People also searched for:

Does T Pallidum antibody cascading test have many false negatives. I know rpr can have false negative due to prozone?

Is the prozone effect with an RPR lab test common? And does the prozone effect also occur with an HIV 1/2 AB lab test? Negative for HIV AB at 14 weeks and had a negative RPR at 17 weeks?

My syphilis test results say: Syphilis Screening Test (what is this?), RPR, TPPA and TMPA IgM ELISA. All negative at 8 weeks, but I am worried about prozone effect. Are these tests prozone proof? Worried also cuz my doc ordered retesting at 12 weeks?

I test Rpr neg at 6weeks then test again and weakly reactive 1:1 at 8 weeks. I treated gonorehea with antibiotic at 4 weeks so is it effect the test at 6weeks for negative. Do i have syphilis now?

Regarding syphilis:could being on 2 antibiotics(metordinazole, ciprofloaxine) in october give a false negative to RPR test done in december?

Telemedicine

Primary Care

Manage Your Conditions

Women's Health

Children's Health

Men's Health

Senior Health

Wellness, Prevention & Lifestyle

Sexual Health

Mental & Behavioral Health

Travel Medicine

Urgent Care

Didn't find what you're looking for?

More of what we treat

Allergies

Antibiotics

Asthma

High Blood Pressure

Prescriptions

Type 2 Diabetes

For Businesses

Company

Health Content

Join Us

Download HealthTap

Questions?