A member asked:

Does t pallidum antibody cascading test have many false negatives. i know rpr can have false negative due to prozone?

A doctor has provided 1 answer

Rpr, vdrl occ false : vdrl and rpr can have false negs. prozone is when there is an overwhelming high antibody titer, such as in secondary syphylis. An FTA absorption test would help to clarify whether there is a prozone as well as dilution of the pt's serum

Answered 11/5/2020

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