Persistent sesamoiditis (after stress rxn); pain (sesamoid &joint) worsens after use. negative mris&x-rays. excercised lst nite & now vry painful. y?

Varies: There are a number of options, probably the most important thing initially would to make sure diagnosis accurate. Orthotics, NSAIDs, and injection are among the treatments used if rest alone does not take care of it; rarely surgery can be done. Don't hesitate to discuss specifics of your case with a specialist.

Strange bones.: Since there are generally two sesamoid bones associated with the great toe, it is important to know if one or both are painful. The tibial one is more often the problem. It is absolutely necessary to X-ray the other foot's sesamoids. The two sides are generally comparable and any variation can mean an injury. Removing part of or the entire sesamoid may be your only choice if all else fails.