HealthTap Online Primary Care Doctors Accepting New Patients
Book a video visit
HealthTap
Telehealth
A member asked:

What's the difference between sle and mctd? & is one worse than the other?

A doctor has provided 1 answer

Both serious: Both are autoimmune diseases; mixed connective tissue disease is less common, still quite variable, and features high levels of antibody against u1 ribonucleoprotein as its signature lab test.

Answered 3/16/2013

5.2k views

Thank

Related Questions

A member asked:

I have SLE and MCTD and in a current flare. My total random Urine protein test came back hi at 17.6 mg/dL. Is this a concern for kidney involvement?

A doctor has provided 1 answer

A member asked:

Can you please discuss the relationship among sle, mctd, anas, anti-rnp, myalgia, and myositis? How common is it to find these concurrent in a person?

A doctor has provided 1 answer

A member asked:

40 yr old pt w SLE and MCTD. Have just been diagnosed w PAH . On the echo the pressure in my right valve is 40 which 30 being normal. Have a severe dry cough and have shortness of breath upon exertion. I want to know how reliable the echo is in evalua

A doctor has provided 1 answer

A member asked:

I had a complement total 50 done with c3-c4 but dr only did total ch50 and it is 60 , i also have autoimmune diseases hashimotos ,sle,ra,mctd and my crp is very very low 5 is this of concern as my dr is not sure , just said it is your autoimm?

3 doctors weighed in across 2 answers

A member asked:

Can CH50 & C1 Esterase Inhibitor be WNL with decreased C3/C4 levels? I've been diagnosed with Anemia, Gatroparesis, SLE & MCTD to date

A doctor has provided 1 answer

Sponsored Content
HealthTap Medical Group does not endorse products or services. Sponsored content revenues support our mission to make health information free and accessible to all.Learn more

People also searched for:

Tested positive for ANA and now further tests show i'm also positive for ENA antibodies - sm b and rnc. Is it more likely to be mctd or sle? Thanks
My diagnosis of SLE was recently changed to MCTD by my Rheumatologist. Was I misdiagnosed for years or can SLE turn into MCTD? Was it something I did wrong?
Two years ago I had a postive ana. Recently I had a comprehensive ANA panel done and by rnp antibodies were 4.4. Could this be sle or mctd?
Could facial paresthesia 3-6x month lasts 1-2 days, cheeks-chin be related to the ai diseases sle, mctd, sclero or dm? I am being tested for these.
I received blood test results with positive RNP and Ana not detected. Is it possible to not have SLE or mctd, or it's definite due to positive RNP?

Telemedicine

Primary Care
Manage Your Conditions
Women's Health
Children's Health
Men's Health
Senior Health
Wellness, Prevention & Lifestyle
Sexual Health
Mental & Behavioral Health
Travel Medicine
Urgent Care
Ask your question
Didn't find what you're looking for?

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.

Ask your question

More of what we treat

Allergies
Antibiotics
Asthma
High Blood Pressure
Prescriptions
Type 2 Diabetes
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
HealthTap
HIPAA logo
HIPAASecure
Soc 2 Type 2 logo
SOC 2 Type 2Certified
JCAHO Accredited
JCAHOAccredited
Member App

Download HealthTap

Video visit and message your doctor

Member App QR Code
Play Store Member LinkApp Store Member Link

Questions?

+1 (888) 828-0841support@healthtap.com
LinkedInTwitter
HomeTermsPrivacyCookiesDMCAHealth TopicsDoctors DirectoryDoctor Q&A by Specialty
Copyright 2026 HealthTap, Inc.