Two years ago i had a postive ana. recently i had a comprehensive ana panel done and by rnp antibodies were 4.4. could this be sle or mctd?

It could be: Unfortunately, there are significant numbers of false positives and false negatives with these types of tests. Only with the guidance of a rheumatologist will you be able to get the right diagnosis. Good luck!

Not necessarily: An abnormal lab test does not necessarily mean that you have a disease. The diagnosis of auto-immune disorders usually requires multiple factors. At least four criteria need to be met for SLE. Visit this site for info. https://www.lupus.org/resources/what-doctors-look-for-to-confirm-a-diagnosis