A member asked:

For treatment of bone metastasis associated with prostate cancer, is xgeva (denosumab) a better one compared to zometa? how much does xgeva (denosumab) cost?

2 doctors weighed in across 2 answers

Slightly better: Xgeva (denosumab) does have some advantages over zometa: quicker administration and no kidney side effects. It is associated with fewer bone complications from cancer than zometa. On the other hand, zometa is now generic, meaning that is a lot cheaper. Neither is a curative treatment for prostate cancer and they are both considered adjunct treatments. Thes small differences may or may not justify its use.

Answered 5/11/2016

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Xgeva (denosumab): Zolmera can have more side effects, that is my view.

Answered 5/6/2013

5.2k views

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