A member asked:

If i'm o positive is it possible for my son to be a negative?

7 doctors weighed in across 3 answers

Yes: People have 2 copies of Rh gene (either + or -). If Dad has at least one Rh- gene and Mom has one Rh- gene then there is chance that an Rh- child can be born. This is clearly explained in the the following link http://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=90&ContentID=P02498

Answered 11/25/2014

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Yes: If you are a heterozygote (an Rh+ and Rh- gene), your phenotype will be positive, but you can pass the Rh- gene to your son. Should the father also pass an Rh-, then your son would have two Rh- genes, and have the Rh- phenotype

Answered 12/15/2014

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Dr. Jon Ahrendsen answered

Specializes in Family Medicine

Yes: Two positive parents can have a negative child. Think of R as positive and r as negative. Everybody has two copies of "R', so the 4 possibilities are: RR, Rr, rR and rr. RR, Rr and rR are all positive, only rr is negative. So if two parents who are Rr and Rr have kids, there is a 75% chance of the child being positive (RR,or Rr, or rR) and a 25% chance the child is negative (rr).

Answered 11/27/2014

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