Not same class: Someone allergic to amoxicillin (in penicillin class) is not considered at high risk for clindamycin allergy (not penicillin class). That does not guarantee that there will not be any reaction. When taking clindamycin, it is a good idea to eat yoghurt or take probiotics to prevent c. dif colitis (a bacterial infection of the colon due to the selective killing of beneficial bacteria).
Answered 2/10/2019
3.7k views
Antibiotic allergy: There is a 15% cross-reactivity beween penicillins and cephalosporin antibiotics, seen in the lab but infrequently seen in patients. Clindamycin is not a penicillin or a cephalosporin, so it is safe to use if you are allergic to either of these categories of antibiotics.
Answered 2/10/2019
3.7k views
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