Question 1

advanced prostate cancer with bone metastasis prognosis?

Accepted Answer

Depends: If the prostate cancer is still responsive to androgen deprivation therapy (adt), which is chemical elimination of testosterone, the patient might have many many years of quality life.  If there are bone metastasis and the disease is no longer treatable by adt, life expectancy with adjunctive chemotherapy is 18 - 24 months typically.

Question 2

treatments for prostate cancer with bone metastasis?

Accepted Answer

Many: The first line of treatment for this is androgen deprivation. In addition, there are medicines which reduce the risk of fractures with Denosumab showing the most efficacy compared to zoledronic acid, however with some risk of significant side effects. For more extensive disease, a newer IV radium therapy has shown improved survival. Localized radiation can be effective for painful foci.

Question 3

dad has advanced prostate cancer with bone metastasis. after orchirectomy, psa down from 270 to 10. shall he start zometa or xgeva (denosumab)? which is better?

Accepted Answer

See Below: Use of bisphosphanates for your dad can be controversial. Here is an excerpt from a recent review article on www.cancernetwork.com which you can use to discuss with your father's doctor to decide what is best for your dad.

http://www.cancernetwork.com/bone-metastases/content/article/10165/105118.

Question 4

what is the prognosis prostate cancer with  metastasis in the bones?

Accepted Answer

Poor: Metastatic prostate cancer, like other disseminated cancers has poor prognosis.  However quality of life can be improved through proper pain managment and hormonal/chemo/radiation therapy.

Question 5

can you explain if it's possible that someone is expected to live for 3 months with prostate cancer with bone marrow metastasis?

Accepted Answer

Yes: Many men with bone meta from prostate cancer live mush longer than three months, some many years.

Question 6

for treatment of bone metastasis associated with prostate cancer, is xgeva (denosumab) a better one compared to zometa? how much does xgeva (denosumab) cost?

Accepted Answer

Slightly better: Xgeva (denosumab) does have some advantages over zometa: quicker administration and no kidney side effects. It is associated with fewer bone complications from cancer than zometa. On the other hand, zometa is now generic, meaning that is a lot cheaper. Neither is a curative treatment for prostate cancer and they are both considered adjunct treatments. Thes small differences   may or may not justify its use.

Question 7

dad is 68, recently diagnosed with advaced prostate cancer with skeletal bone metastasis. what kind of hormone therapy shall he use?

Accepted Answer

Multiple available: There are multiple hormonal and non-hormonal therapies available. Your dad desperately needs a visit to a urologist and a cancer specialist, and maybe a radiotherapist. Get him in for a visit quickly!

Question 8

what do you suggest if my grandfather 94yrs old having prostate cancer and also has metastasis in pancrease (pancrelipase) and bones ,?

Accepted Answer

Comfort: No major interventions.
Kindness. Caring, listening, loving!

Question 9

my grandfather 94yrs old having prostate cancer and also has metastasis in pancrease (pancrelipase) and bones. treatment options?

Accepted Answer

No treatment: In spite of your grandfathers clinical condition, the pattern of behavior of prostate cancer after 80 , for the most part typified by an indolent form of metastasis.  One uses drugs like Lupron (leuprolide) to reduce hormones but at his age there are probably little or no hormones secreted.  Chemo such as Taxol not utilized.  Therefore he should live normal expected time for a 90yo without further intervention

Question 10

my dad is 68 years old. recently, he was dignosed with advanced prostate cancer with skeletal bone metastasis. what kind of hormone therapy shall he use? is orchiectomy ok?

Accepted Answer

Yes: Orchiectomy is nearly instantly effective in reducing testosterone levels and can be done as an outpatient. Alternatives include injections (lhrh agonists) to reduce testosterone levels. These are relatively expensive over the long term, but preserve the testicles which is why many men prefer this option. Surgery is permanent whereas shots can be withheld, but permanent may be best with bone mets.

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Doctor answers about:

Prostate cancer bone metastasis symptoms

A member asked:

Advanced prostate cancer with bone metastasis prognosis?

A member asked:

Treatments for prostate cancer with bone metastasis?

A member asked:

Dad has advanced prostate cancer with bone metastasis. after orchirectomy, psa down from 270 to 10. shall he start zometa or xgeva (denosumab)? which is better?

A member asked:

What is the prognosis prostate cancer with metastasis in the bones?

A member asked:

Can you explain if it's possible that someone is expected to live for 3 months with prostate cancer with bone marrow metastasis?

A member asked:

For treatment of bone metastasis associated with prostate cancer, is xgeva (denosumab) a better one compared to zometa? how much does xgeva (denosumab) cost?

A member asked:

Dad is 68, recently diagnosed with advaced prostate cancer with skeletal bone metastasis. what kind of hormone therapy shall he use?

A member asked:

What do you suggest if my grandfather 94yrs old having prostate cancer and also has metastasis in pancrease (pancrelipase) and bones ,?

A member asked:

My grandfather 94yrs old having prostate cancer and also has metastasis in pancrease (pancrelipase) and bones. treatment options?

A member asked:

My dad is 68 years old. recently, he was dignosed with advanced prostate cancer with skeletal bone metastasis. what kind of hormone therapy shall he use? is orchiectomy ok?

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