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Blood disorders
Monoclonal gammopathy of undetermined significance

Monoclonal gammopathy of undetermined significance

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Increased immunoglobulin ( antibody) level in small amounts from single clone of plama cells ( present in bone marrow) in small amounts without causing any symptoms unlike in multiple myeloma.

Dr. Alok Agrawal reviewed this

36 years experience

Is a type of:

Blood disorders

How long it usually lasts:

Chronic (lasts years to lifelong)

How common it is:

Very rare

Other treatments

Counseling

Tests

Creatinine
Ionized calcium
Complete blood count
Protein electrophoresis
24 hour urine protein electrophoresis
Load more

Risk factors

Personal

Exposure to radiation

Related questions

A 47-year old asked:

What's monoclonal gammopathy of undetermined significance?

1 doctor answer • 1 doctor weighed in

A 48-year old asked:

Can i treat a possible monoclonal gammopathy of undetermined significance at home?

1 doctor answer • 1 doctor weighed in

A 28-year old male asked:

What is the definition or description of: monoclonal gammopathy of undetermined significance?

2 doctor answers • 2 doctors weighed in

A 21-year old asked:

What is monoclonal gammopathy of undetermined significance (mgus)?

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A 42-year old asked:

What is monoclonal gammopathy about?

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A 37-year old asked:

What can cause monoclonal gammopathy?

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A 40-year old female asked:

What are possible causes of highly elevated ImM levels with low ImG levels with no monoclonal gammopathy present?

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A 40-year old asked:

Is mononuclueosis associated at all with monoclonal gammopathy?

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A 54-year old female asked:

What is an IgA heavy chain monoclonal gammopathy?

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A 51-year old female asked:

IgA lambda monoclonal gammopathy meaning?

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A 41-year old asked:

Can monoclonal gammopathy cause osteomyelitis?

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A 36-year old asked:

Is mononucleosis associated with monoclonal gammopathy?

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A 65-year old male asked:

Are any of (1) overlap myeloproliferative/myelodysplastictiy disorder (2) monoclonal B cell lymphocytosis or(3) monoclonal gammopathy ever familial?

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A 33-year old male asked:

Can you have a monoclonal gammopathy(and not mgus) while having a normal CBC w/differential?

2 doctor answers • 6 doctors weighed in

A 40-year old female asked:

How reliable are blood tests that look for monoclonal gammopathy in elevated ImM levels ? Are false negatives possible?

1 doctor answer • 2 doctors weighed in

A 29-year old female asked:

Free kappa light chain is high, FLC ratio is 2.205, no monoclonal gammopathy. IgA 389.43, lgM 125.95 and lgG 1771.02 H. Should we be worried? Thanks.

1 doctor answer • 1 doctor weighed in

A 59-year old male asked:

Can a IgM kappa light chain monoclonal gammopathy turn into macroglobulinemia?

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A 49-year old male asked:

I had a blood test done, what does it mean? Kappa monoclonal gammopathy. Is this rare? Does this mean cancer? Is this anything to worry about?

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A 59-year old male asked:

Can monoclonal IgM kappa light chain gammopathy turn into multiple myeloma?

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A 64-year old male asked:

I understand that monoclonal gammopathy can cause a high CRP. As a matter of interest, does it typically elevate the WBC as well?

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A 38-year old female asked:

I just checked my health summary online and the doctor noted hyperglobulinemia and monoclonal gammopathies.I am also referred to a hematologist. What could be its meaning?

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A 31-year old male asked:

Slightly elevated beta fraction from serum protein electrophoresis. Beta 1.07 (high) (0.52-0.98) increased beta fraction, no monoclonal or polyclonal gammopathy seen. Immunofixation normal.

1 doctor answer • 2 doctors weighed in

A 46-year old female asked:

I had a serum immunofixation and serum electrophoresis run and the interpretation was suspicious of monoclonal gammopathy and IgG lambda. What does this mean? The beta and gamma globulin where at 0.6 and 0.7 g/dl?

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A member asked:

My husband is diagnosed with IgA lammda monoclonal gamopathy.The blood report says m-spike seen in beta region .Is this curable?

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A 37-year old asked:

What is the treatment for gammopathy?

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A 41-year old female asked:

What is mild polyclonal gammopathy that's what the dr said I have but I haven't seen him yet?

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A 48-year old female asked:

My IgM level went from normal to very low. Down to 28. What is going on? I am being followed for biclonal gammopathy. Should I worry

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A 52-year old female asked:

I was diagnosed with RA a couple years ago. Just did ife and pe serum and it is suggested an apparent polyclonal gammopathy. What is that?

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A 27-year old female asked:

How does having polyclonal gammopathy correlate with lupus- I have lupus and polyclonal gammopathy does having this mean you have a more severe form of lupus, they did an spep be4 lupus and i had that?

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A 25-year old female asked:

Does Ebv (mono) cause polyclonal gammopathy?

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