A 21-year-old member asked:
What is monoclonal gammopathy of undetermined significance (mgus)?
2 doctor answers • 3 doctors weighed in
Dr. Michael Thompsonanswered
Hematology and Oncology 22 years experience
Lab finding, pre-MM: Mgus is monoclonal gammopathy of undetermined significance.
It was called "benign monoclonal gammopathy" until ~1975 when robert kyle published an article in the nejm.
Myeloma is thought to evolve from mgus at about 1% per year.
Mgus risk factors can increase or decrease that risk.
Created for people with ongoing healthcare needs but benefits everyone.
6.5k viewsAnswered >2 years ago
Dr. Stephen Nogaanswered
Medical Oncology 36 years experience
Blood & urine tests: Mgus is the presence of an abnormal protrein in the blood made by a type of white blood cell called a plasmacyte. In most cases, it is at a low level and is something that just has to be followed. However, it can be the precursor of the disease called multiple myeloma and as such a hematologist or medical oncologist will order tests to rule this out which may include blood, urine and simple x-rays.
Created for people with ongoing healthcare needs but benefits everyone.
6.4k viewsReviewed >2 years ago
Similar questions
A 47-year-old member asked:
What's monoclonal gammopathy of undetermined significance?
1 doctor answer • 1 doctor weighed in
Dr. Ahmad M Hadiedanswered
Orthopedic Surgery 51 years experience
MGUS: Is a common precancerous condition affecting people 50 years of age and older. It was first described by mayo clinic researchers in 1978 and is characterized by the presence of an abnormal protein in the blood called a (monoclonal) protein or m protein.Mgus has a small risk (1 percent each year) of progressing to a blood cancer called multiple myeloma or a related condition.
Created for people with ongoing healthcare needs but benefits everyone.
5.5k viewsAnswered >2 years ago
Last updated Jun 7, 2019
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