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A member asked:

Can monoclonal igm kappa light chain gammopathy turn into multiple myeloma?

A doctor has provided 1 answer
Dr. Liawaty Ho answered

Specializes in Hematology and Oncology

It can: Yes, it can . It will depend on how much is the quantity of the monoclonal proteine, how many plasma cells on the bone marrow and ultimately whether one has end organ damages/ whether some other organs are affected significantly by the monoclonal protein. That is why some blood work, imaging study and bone marrow biopsy need to be done.

Dr Hughes agreed

Answered 4/1/2019

5.2k views

Thank

Related Questions

A member asked:

Serum free light chain test shows normal kappa (8.7mg/dl), low lambda (3.80), high kap/lam ratio (2.31). Serum $ urine electrophoresis show no monoclonal protein, nor does serum immunofixation. Likely MGUS, myeloma, or admyloidosis? CBC/met panel ok.

2 doctors weighed in across 2 answers

A member asked:

Can you explain what this might mean: "apparent polyclonal gammopathy: igm. Kappa and lambda increased". Immunoglobulin m is also high at 437.?

3 doctors weighed in across 2 answers

A member asked:

Multiple myeloma at age 22? Possibility of IgG kappa monoclonal band is observed in my blood work. I have the symptoms of mm. Is this possible at 22?

4 doctors weighed in across 2 answers

A member asked:

I've had an elevated IgM for 1 year along with systemic symptoms. No monoclonal antibody, free light chains or Bence jones protein in urine so myeloma was eliminated and my infection screen and FBC is normal. What other diseases could cause high IgM?

A doctor has provided 1 answer

A member asked:

What is the difference in testing an IgG and IgM bands for Lyme versus multiple myeloma?

A doctor has provided 1 answer

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People also searched for:

Can a IgM kappa light chain monoclonal gammopathy turn into macroglobulinemia?
I am 45 and male. Serum IgA at 472 mg/dl and an apparent polyclonal gammopathy IgA kappa/lambda typing appear increased. Serum free light chain: high kappa 35 mg/L, lambda normal 17.8 mg/L and a ratio of 1.97. Is this Myeloma? No M-protein found?
Resent blood work states IgM 875, an appearant polyclonal glammopathy IgM, kappa and Lambda light chains appear increased. Possible Multiple myeloma?
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