is pernicious anemia genetically caused?

Question

How does pernicious anemia cause people to have achlorhydria?

Answer 1

Not usually: Pernicious anemia is caused by vitamin B12 or Folic Acid deficiency. It may be associated with gastrointestinal or liver problems and should be investigated by your physician.

Answer 2

Strong genetic: association! Can run in families!

Answer 3

Yes: The first step is testing you for sickle cell carrier status. If not a carrier then no further testing needs to be done. If you are a carrier then the next step is check the father of the baby. If he is unavailable you could have his parents tested. If neither are a carrier then the father can not be a carrier either. If they are carriers then the fathers chances are 50% he is also.

Answer 4

Only blood tests.: People with sickle cell anemia usually are identified very early in childhood, due to symptoms. Sickle cell carriers, have no symptoms and can only be identified by blood test. Inheriting sickle cell disease requires getting a sickle gene from both parents. If you are a carrier and your husband is too, there is a 1 in 4 chance of a child inheriting the disease.

Answer 5

Anemia: Yes. The fetus during pregnancy draws many substances from the mother, one of which is iron. If the mother has a poor intake of iron, then she is prone to iron deficience anemia. Also if the mother has a large amount of blood loss during delivery, this can cause anemia.

Answer 6

Yes: The developing baby draws a lot of nutrients, including iron. Most women gain water weight during pregnancy, which lowers the blood concentration. A fair amount of blood is lost during the labor process. These all contribute to anemia of pregnancy. Check with your doctor to make sure you are getting enough nutrients in your diet.

Answer 7

Kidney disease: Diabetes, especially if not controlled, will negatively affect kidney function, notably with respect to that organ's vital function in stimulating blood cell production. The kidneys do so by secreting a hormone that leads to red cell production.

Answer 8

Only kidney disease: So if anemic, likely not related to diabetes look for other cause! see md.

Answer 9

Ask ur Hematologist: Dietary cyanate, from foods containing cyanide derivatives, has been used as a treatment for sickle- cell anemia. In the laboratory, cyanate and thiocyanate irreversibly inhibit sickling of red blood cells drawn from sickle cell anemia patients. However, the cyanate would have to be administered to the patient for a lifetime, as each new red blood cell created must be prevented from sickling.

Answer 10

No: Cyanate and thiocyanate should not be used to treat sickle cell anemia. Patients with sickle cell disease are treated with hydroxyurea. For younger patients they should be treated with stem cell transplantation and they will be cured. Gene therapy, a technique in which normal genes are implanted in precursor cells (cells that produce blood cells), is being studied.

Answer 11

Types os SIckle Cell: From nih, division of blood diseases and resources: sickle cell disease-ss: 65% of us patients; genotype s/s sickle cell disease-sc: 25% of us patients; genotype s/c sickle cell disease-s beta + thalassemia: 8% of us patients; genotype betas/ beta + thalassemia sickle cell disease-s beta 0 thalassemia: 2% of us patients; genotype betas/ beta 0 thalassemia.

Answer 12

Two: Sickle cell anemia occurs when 2 abnormal hemoglobin genes are present and a person's body produces sickle cell hemoglobin exclusively. 1 sickle cell gene and a normal gene produce sickle trait, which has no symptoms. Other abnormal hemoglobin genes can combine with a sickle cell gene and produce other types of anemia. There are several other genetic hemoglobin abnormalities.

is pernicious anemia genetically caused?

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