Yesterday my husband was awakened during the night with severe pain in one knee. hurts most when bending this mornining the knee is hot and red.

Many possibilities: Could be an infection, gout, a response to an earlier trauma. He needs to be seen by a physician asap.

Gout or infection: A sudden hot red joint in an adult male is most likely gout if there's no trauma. But he could have an infection - call your primary doctor. In the meantime, if it is usually safe for him, Ibuprofen can help (800 mg, or 4 of the otc pills) three times a day while you await being seen by the doctor.

Get in to see doctor: He may have an infection so he should be seen immediately. It may also be some form of arthritis but infection needs to be considered first.

Knee Pain: An acute onset of knee pain that is hot and red needs urgent attention. Concern is for infection or inflammatory arthritis. Please get it seen today.