45 to 80 hours: The half-life of Depakote er is 9-16 hours. This is the time for 1/2 the drug to be excreted from the body. After 5 half-lives more than 95% of the drug has been removed from the body. Note that other drugs or medical conditions such as liver or kidney disease could affect this estimate.
Answered 7/8/2017
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