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Oakland Gardens, NY
A 25-year-old male asked:

what drug has the least side effects to treat pain...gabapentin lyrica (pregabalin) or cymbalta?

4 doctor answers10 doctors weighed in
Dr. Pavel Conovalciuc
Family Medicine 23 years experience
All : All of these medications have their side effects and different people react differently to these drugs. Lyrica (pregabalin) and Neurontin being sister molecules have somewhat similar side effect profile, though. In my practice, most of my patients have been able to tolerate all these medications ok in most cases.
Dr. Brian Le
Dr. Brian Le answered
Pain Management 17 years experience
Similar: All of these medications have similar side effect profiles. The side effects you might experience is different from person to person.
Dr. Parham Gharagozlou
Sleep Medicine 9 years experience
Would pich gabapenti: Any day i would pick Gabapentin over other based on clinical experience with side effects unless Gabapentin is not working well for patient.
Dr. Bennett Machanic
Neurology 52 years experience
Variable: Cymbalta causes nausea in about 40%, and others do not, but both Lyrica (pregabalin) and Gabapentin cause weight gain, foot edema, drowsiness, dizziness, and occas stomach upset. If you wish gabapentin, newer once daily preps such as Horizant and Gralise seem to have slightly fewer side effects.

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Last updated Sep 26, 2017
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