A member asked:

What drug has the least side effects to treat pain...gabapentin lyrica (pregabalin) or cymbalta?

10 doctors weighed in across 4 answers

All : All of these medications have their side effects and different people react differently to these drugs. Lyrica (pregabalin) and Neurontin being sister molecules have somewhat similar side effect profile, though. In my practice, most of my patients have been able to tolerate all these medications ok in most cases.

Answered 9/26/2017

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Dr. Brian Le answered

Specializes in Pain Management

Similar: All of these medications have similar side effect profiles. The side effects you might experience is different from person to person.

Answered 9/27/2013

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Dr. Parham Gharagozlou answered

Specializes in Sleep Medicine

Would pich gabapenti: Any day i would pick Gabapentin over other based on clinical experience with side effects unless Gabapentin is not working well for patient.

Answered 6/25/2014

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Variable: Cymbalta causes nausea in about 40%, and others do not, but both Lyrica (pregabalin) and Gabapentin cause weight gain, foot edema, drowsiness, dizziness, and occas stomach upset. If you wish gabapentin, newer once daily preps such as Horizant and Gralise seem to have slightly fewer side effects.

Answered 9/26/2017

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