Is it more advisable to get a colonoscopy at a surgical outpatient center vs a doctor's office? is propofol safe to use as anesthesia during it?

Basically yes: While most healthy people can safely have a colonoscopy in a private office, an outpatient surgical center likely has greater support in the unlikely event that problems occur. Propafol is quite safe and preferable when i look at the feedback from my own patients who have had both varieties of anesthesia. If you are paying out of pocket, propafol will be more expensive.

Both safe: But the more medical issues/problems the better off at an ambulatory center but it really depends on what the comfort level of the office people as well as what kind of problems/complication they are prepared to handle.

Your choice: The anesthetic propofol, in the hands of a trained anesthesia provider, is a very safe anesthetic agent. The procedure can be done at a doctor's office, or an ambulatory clinic, as long as there are sufficient safeguards in place in the case of emergency.