Get Virtual Care
For Businesses
About Us
A member asked:
6y/o on 22.5 methotrexate injrctions for 3mths for jra has occasional swelling but has stiffness &pain almost daily what should be next step? new meds
4 doctors weighed in across 2 answers
See below: Your doctor could try increasing the Methotrexate to 25, but they may considering adding a biologic such as Enbrel or Orencia (abatacept) next.
Answered 10/24/2017
5k views
Add a TNF-inhibitor: A dose of 22.5mg of weekly Methotrexate is a large dose for a 6yo (i rarely go above 15mg weekly for small children).The side effects and toxicity increase with marginal if any benefit. Enbrel, humira, or Remicade (infliximab) should be added immediately. There's absolutely no reason not to add one of these.They have fewer side effects and work better.Also lower Methotrexate dose to 15mg but use both.
Answered 6/30/2014
5k views
Related Questions
A member asked:
Better to be on methotrexate and hydroxychloroquine or methotrexate and a biologic when treating jra? Methotrexate only doesn't help
5 doctors weighed in across 2 answers
A member asked:
What is the highest dose of methotrexate injections can a (50lbs)6 year old be on when treating jra? She on 22.5mg for 3wks and no improvement yet
A doctor has provided 1 answer
A member asked:
What is a low dose, moderate dose and high dose of methotrexate to start out on for jra ?
A doctor has provided 1 answer
A member asked:
Is 22mg of methotrexate injections a low or high dose to start off with a 6 year old with jra?
A doctor has provided 1 answer
People also searched for:
Child has only occasional swelling but stiffness and pain almost daily from jra she still plays but it hurts her already on metho what shoukd i do?
6y/o has jra/jia and on 22.5 methotrexate injections for 3 months and lil improvement but rheumo won't add or change meds. What do I do?
Child on methotrexate 25mg rheumo just added plaquenil (hydroxychloroquine) for jra. How long will it take for plaquenil (hydroxychloroquine) to work? If this doesn't help what next step?
How long before methotrexate works for jra? How long do u need to be on it before adding another med like enbrel (etanercept)?
Child has JRA on methotrexate remicaid NSAID just got off a round of steroids knee still really swollen in similar situations what is next step?
Didn't find what you're looking for?
90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.
Ask your questionMore of what we treat
Download HealthTap
Video visit and message your doctor
