A member asked:

Better to be on methotrexate and hydroxychloroquine or methotrexate and a biologic when treating jra? methotrexate only doesn't help

5 doctors weighed in across 2 answers
Dr. Lokesh Guglani answered

Specializes in Pediatric Pulmonology

Depends on severity: Since you have already been on Methotrexate and its not helping you get complete relief from symptoms, further addition of therapies will depend on severity of your current symptoms. Hydroxychloroquine is milder in efficacy as compared to biologics & both have different side effect profiles. Talk to a rheumatologist who can assess your clinical course & treatment needs & then advise accordingly.

Answered 4/17/2016

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Jra treatment: Methotrexate and biologic is considered best practice in pediatrics when more than one agent is needed for aggressive treatment.

Answered 6/28/2014

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