A member asked:

What about cymbalta (duloxetine) discontinuation syndrome?

6 doctors weighed in across 3 answers

Be very careful: Cymbalta, (duloxetine) like any ssri or snri, can create a physical dependency because of the effect they have on neurotransmitters. Everyone should be withdrawn from these drugs very carefully & cautiously. 3 weeks is the minimum one should take to reduce by each incriminate. Serious side effects, including suicide, have been reported when not properly.

Answered 8/26/2018

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It can: Discontinuation syndrome is seen with Cymbalta (duloxetine) and needs to monitored. It can avoided by decreasing slowly before discontinuing. The usual symptoms include but not limited to are dizziness, confusion, yawning, anxiety and irritability.

Answered 4/29/2019

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Dr. Alan Ali answered

Specializes in Psychiatry

Cymbalta (duloxetine): Dizziness, lightheadedness, restlessness, insomnia, stomach upset.

Answered 3/22/2020

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