How does cymbalta (duloxetine) work?

Cymbalta (duloxetine): Is an nsri, or a norepinephrine/serotonin reuptake inhibitor. This means that Cymbalta (duloxetine) slows the breakdown of both of these neurotransmitters, which allows them to have a longer effect.

Cymbalta (duloxetine): It's actions on norepinephrine & serotonin helps releave symptoms of depression & fibromyalgia.

Terrible side effect: Side effects are horrrific.

Very well for many: Cymbalta (duloxetine) is a serotonin-norepinephrine specific reuptake inhibitor- a medication that blocks the reuptake of these chemicals from the synapse, the area between two nerve cells (axon and dendrite). This leads to changes that would take way more than 400 characters to describe. Essentially it helps the brain to process information better, decreasing depression, anxiety and pain in many patients.