A member asked:

Can you please tell me genetic causes of early onset obesity?

A doctor has provided 1 answer

Mostly complicated: There are known genetic causes of childhood obesity. One is prader-willi syndrome, which is rare but causes morbid obesity in childhood. Even more rare is leptin deficiency. There are other rare causes, often associated with other conditions. Most obesity is "polygenic", meaning multiple genes affect the trait, which makes it hard to pinpoint the precise cause.

Answered 7/4/2013

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