We rarely switched a 40 mg of simvastatin to a 40 mg of rosuvastatin, especially when lipid panel was not checked with the previous medication. For a patient with history of coronary heart disease, especially with type 2 diabetes mellitus, we prefer the LDL cholesterol as low as possible but not with total cholesterol less than 100. By strength, simvastatin 40 mg = 20 mg or less of rosuvastatin.
Answered 9/7/2023
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