Dearborn, MI
A 36-year-old male asked:

My lupus flares are skin manifestation only(malar rash)plus fatigue.but esr n crp keeps coming normal including ana.on plaquenil (hydroxychloroquine). was dx not correct?

2 doctor answers6 doctors weighed in
Dr. David Weissman
Internal Medicine 26 years experience
Lupus: Lups is a very difficult diagnosis to make correctly, since there are many diagnostic criteria, and test results are not 100% accurate for this condition. However, as the malar rash and fatigue are your only symptoms, I would at least get a second opinion from a board-certified rheumatologist, perhaps who specializes in Lupus. Since it's a chronic condition, you want to be sure you have it right.
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Dr. Robert Lowe
Pediatric Rheumatology 19 years experience
Maybe, maybe not...: You may have a type of lupus called subacute cutaneous lupus erythematosus(SCLE)which can often be a milder form of systemic lupus(SLE) and can be seen with normal inflammatory markers (ESR).Can also be Sjogren's. However,half of people with SCLE also meet criteria for full blown SLE. SCLE patients can have more serious organ involvement than just skin that should be checked for.See rheumatologist
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Last updated Sep 11, 2023
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