When do most adverse reactions happen after your covid vaccine? i had the first round about 3 hours ago and so far, only a sore arm and severe anxiety?

The worst reactions (anaphylaxis) would be expected within the first half hour. The common "feel bads" occur over the next 48 hrs or so, some feel bad for a week. Each person has an individual response. Your anxiety likely makes any issue worse.

Dr Ferguson provides a good timetable guide. The severe anxiety would appear to be your biggest problem and needs to be handled. You could obtain a few sessions of biofeedback therapy or cognitive-behavior therapy. Would try to eschew sedative/ tranquilizers and learn techniques which can be applied in the future.

Address anxiety with non medication alternatives and discuss with your PCP. If medication is indicated, combine with non medication strategies. The vaccination administration may cause injection site soreness, but if there is prolonged pain, fever or redness, please see a physician. A virtual consultation is available on Healthtap. I agree that most reactions occur in the first 48 hours.

Some people get minor aches and a low fever for a day or so. Acetaminophen is usually sufficient to relieve the symptoms. Do not take more than 4 gm and no alcohol. Wish you good health!