(For an expert's answer to this pertinent question, it's best to consult with an infectious disease specialist.) A negative antibody test after vaccination might not test for the antibody to the segment of RNA (or other segment) used in the vaccine. Also, there are circulating antibodies and cellular immunity; the tests might not test for the immunity stimulated by the vaccine.
Answered 10/31/2021
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Assuming that you have a healthy immune system (no immunosuppressive drugs, no frequent pneumonia or sinus infection), you most likely have had a fine immune response. If the recent COVID test was recent to the actual vaccine, the antibody levels may still be rising. It is not recommended to check antibody levels post vaccine.
Answered 10/31/2021
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Different antibodies: The CDC recommends against using antibody tests to judge whether a person is immune after a vaccine, and one reason is that a vaccine may produce antibodies to one part of the virus while the antibody tests measure antibodies that target a different part of the virus. So a natural infection may produce antibodies that those tests measure while the vaccine may produce antibodies that they don't.
Answered 10/31/2021
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The adaptive immune system is very complex, and antibody testing will not cover the complex memory cells, and responses of T cells and B cells, especially plasma cell potential reactions. Agree with CDC, as measuring IgM and IgG over a slice of time is usually misleading, and not helpful. Furthermore, it disregards IgA involving nasal and sinus mechanisms.
Answered 10/29/2021
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