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A 34-year-old male asked:

Is it ok to take an aleve for a headache if i'm taking omeprazole?

1 doctor answer1 doctor weighed in
Dr. Yvette Kratzberg
Pediatrics 25 years experience
Not Advisable: Not advisable to take naproxen together with omeprazole. Using these medications together may affect the enteric coating of naproxen, causing the medication to be released too early in the body. This can make naproxen less effective. Try taking them at least 8 hours apart to prevent this effect.

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Last updated Jun 26, 2020

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