If a patient is toxic on clozaril (clozapine) therapy can he get edema?

Not likely: Edema is not listed as a side effect from clozaril (clozapine).

Seek further care!: Cardiotoxicity is a rare but serious side effect from clozapine. If this is a problem, one could experience increased edema, particularly in the lower extremities. I would seek professional advice from a trained clozapine provider. Checking a clozapine level could be helpful here. Would also be good to look for other causes of edema or other underlying medical comorbidities.

Clozaril: Agree with both Dr. Majeroni & Dr. Pease, While edema is not listed as a side effect of Clozaril it could occur indirectly. It is essential that blood work be done at least monthly if taking Clozaril. Clozapine is an antipsychotic medication used as a treatment for refractory Schizophrenia & for Schizophrenia or Schizoaffective Disorder that can have serious side effects.