A member asked:

Before starting duloxetine 60mg i was 242.5 lbs and have remained similar weight since, however, my waist has gone 107cmto124cm. could duloxetine cause something eg swelling to explain this? or perhaps an interaction between clozapine and duloxetine?

A doctor has provided 1 answer

Probable Interaction: There is a well established interaction between duloxetine & clozapine leading to various abnormalities including elevated clozapine blood levels and blood chemistry abnormalities. Anyone on this combination should be monitored closely by their prescriber(s) including lab studies on blood chemistries & clozapine serum levels along with the routine blood counts required on clozapine.

Answered 12/7/2016

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