See below : Ibuprofen and naproxen: both Nonsteroidal anti-inflammatory drugs (NSAIDs). Though in the same class with similar benefits, risks, and potential side effects, some pts find that one drug works better or is better tolerated than the other. Naproxen: longer elimination half-life (17 hrs) vs ibuprofen (2-4 hrs): Would generally be safe to take ibuprofen 12- 24 hrs after your last naproxen dose.
Answered 6/14/2018
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