A 31-year-old male asked:

Kappa/lambda flc ratio high (2.75) w/ normal k(10.21mg/dl) & low l(3.68mg/dl). hem-onc unsure if ratio implies k monoclonality since serum/urine ife ok & neither chain is elevated. could monoclonal k be suppressing l? iga a bit high igg &igm a bitlow

2 doctor answers5 doctors weighed in
Dr. Gurmukh Singh
Pathology 51 years experience
Useless test: K/L ratio is not a useful test. About one third of patients without monoclonal immunoglboulin have an abnormal ratio, usually with kappa excess. If you must, the next step would be a bone marrow examination. You may consult this article that I wrote: https://www.ncbi.nlm.nih.gov/pubmed/27473738 At your age you are unlikely to have myeloma.
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Dr. John Goldman
Rheumatology 57 years experience
We need more inform: We need more information. next up is a bone marrow but I really doubt this is legacy. It would certainly be very unusual your age
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Last updated Nov 27, 2017
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