A 31-year-old male asked:
Kappa/lambda flc ratio high (2.75) w/ normal k(10.21mg/dl) & low l(3.68mg/dl). hem-onc unsure if ratio implies k monoclonality since serum/urine ife ok & neither chain is elevated. could monoclonal k be suppressing l? iga a bit high igg &igm a bitlow
2 doctor answers • 5 doctors weighed in
Pathology 50 years experience
Useless test: K/L ratio is not a useful test. About one third of patients without monoclonal immunoglboulin have an abnormal ratio, usually with kappa excess. If you must, the next step would be a bone marrow examination. You may consult this article that I wrote: https://www.ncbi.nlm.nih.gov/pubmed/27473738
At your age you are unlikely to have myeloma.
833 viewsReviewed >2 years ago
Rheumatology 56 years experience
We need more inform: We need more information. next up is a bone marrow but I really doubt this is legacy. It would certainly be very unusual your age
819 viewsAnswered >2 years ago
Last updated Nov 27, 2017
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