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A member asked:
Serum free light chains increased ratio normal. lambda immunofixation with 4% m spike in beta 2 region in urine only. recommended next step 4 anemia?
A doctor has provided 1 answer
Spike in UPEP: If you have an abnormal M spike on your urine protein electrophoresis (UPEP), that suggests there is some abnormal cells making excess gamma globulin ( a monoclonal gammopathy). A next step would normally include a bone marrow aspirate and biopsy - this reveals what the abnormality of the blood forming cells causing this is.
Answered 2/25/2018
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