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Mesa, AZ
A 59-year-old female asked:

I have inconsistent tests that lean toward multiple myeloma or mgus. first xray lytic lesion; globulin series serum & urine monoclonal positive to gamma; 24 hr electopherurine neg; beginning anemia; bun off; other small abnormals. bone survey neg.

2 doctor answers2 doctors weighed in
Dr. Dan Fisher
Internal Medicine 28 years experience
Complicated question: I am not going to be able to give you a better answer here - too complicated. You should have had a good discussion with your oncologist about what this all means. If you have a lytic lesion it may be reasonable to obtain biopsy.
Dr. Hernani Cualing
Pathology 31 years experience
Need second opinion: The criteria for myeloma vs Mgus changed recently but both changes include exact percentages and size of lytic bone lesions. Your data as you summarized are not adequate and since mgus vs multiple myeloma are like dawn and day, you need to be seen and your precise numbers verified. That said, please see hemeonc in centers experienced in myeloma dx,management,and treatment.

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Last updated Jul 24, 2016

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