A member asked:

Is lithium more dangerous than using a combination of lamictal and tegretol to treat bipolar?

3 doctors weighed in across 2 answers

Suggest: Lithium if handled properly can be very safe and effective, as we can easily detect appropriate therapeutic blood levels. Tegretol has loads of side effects and potentially longterm problems, and I would not recommend it for anyone, but I like lamotrigine, which is usually well tolerated. Ask your doctor to discuss positives and negatives, and make a decision.

Answered 2/26/2016

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Dr. Eric Weisman answered

Specializes in Neurology

Lithium vs lamictal: For bipolar it depends on the individual situation. Lamictal needs to be titrated slowly to reduce the risks of Stevens Johnson Syndrome and other serious rashes. lithium and Tegretol can more rapidly brought to therapeutic levels. ( as can Depakote) One must watch for long term side effects like low sodium with Tegretol and kidney or thyroid issues witty Lithium ( weigh risks with your MD )

Answered 5/3/2016

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