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A 50-year-old male asked:

Have taken klonopin 1.5, tegretol 600, lamictal 100, cymbalta (duloxetine) 60 bipolar-ocd for 8 years-liver functions fine-how long before i have liver problems?

2 doctor answers2 doctors weighed in
Dr. Aruna Adaikkalam
Internal Medicine 38 years experience
Not everybody has it: If for 8 years on all these medications you didn't have issues , it is likely that you will not have anything bad in the future. Also not all the medications in this list cause liver fn. abnormalities. Get periodic check up of liver enzymes once in 6 months. That should be enough, which could be ordered by your PCP.
Dr. Stephen Southard
Internal Medicine 15 years experience
Most likely never: While each of these medications have some potential to affect liver function tests - it being greatest in Tegretol - most of the changes tend to be benign(or harmless). I would worry to much, particularly if you doctors continue to monitor this periodically. Best of luck.

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Last updated Feb 26, 2016

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