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A 33-year-old female asked:

Can i take zanaflex (tizanidine) and zyrtec d together? treating a sinus headache.

2 doctor answers2 doctors weighed in
Dr. John Goldman
Rheumatology 57 years experience
There is a precautio: Caution is advised due to the combination of these two medications can increase the risk of ccentral neurological sytem depression and can lead to psychomotor impairment
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Alvin Lin
Geriatrics 32 years experience
Not appropriate use: Zanaflex (tizanidine) is a muscle relaxer (http://www.drugs.com/zanaflex.html) so it's not intended for use in treating sinus headaches. Moreover, use of Zanaflex (tizanidine) w/ZyrtecD (antihistamine w/decongestant) runs risk of drowsiness, dizziness, lightheadedness, difficulty concentrating, and impairment in thinking and judgment. You didn't ask but definitely don't recommend concomitant alcohol. http://goo.gl/w30maz
Created for people with ongoing healthcare needs but benefits everyone.

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Last updated Aug 26, 2019

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