4yo has severe laryngomalacia, sleep apnea, aspirates, history of hypotonia & gross motor delay, mthfr, midline defects, spd, possible autism. causes?

Genetic?: In addition to the known MTHFR defect, this may be associated with genetic syndrome. Consultation with a geneticist is recommended. Depending on how well he does in the next few months-years, whole exome genetic sequencing (now more readily available due to technological advances) may be considered if it is felt that knowing cause will guide management.

Mgt, workup: The severe laryngomalacia can cause and contribute to sleep apnea and aspiration. I would suggest an evaluation by ENT and a sleep study to evaluate the need for CPAP. Speech and development can help with coordination/swallowing mechanisms. A virtual appointment: healthtap.com/DosanjhMD Code: NCYHPZ