Yes and depends ..: In my clinical experience about 3/4 of the patients with ASD have at least one mutation in the mthfr gene - either the a1298c or c677t variants. When 2 mutations are present at the same location (homozygous), then the effects on health are greater. Homocysteine level is less predictive because many other genes affect it. Appropriate treatment has been helpful for mood, learning and behavior.
Answered 6/10/2014
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More research needed: The mutation mthfr has been implicated in a variety of psi strip illnesses from schizophrenia to down's syndrome. Homocysteine levels san be normal in autism. At this juncture no one has been able to find the cause of autism much more research is needed.Take mthfr with a grain of salt. There is absolutely no evidence that it can cause autism.
Answered 4/5/2013
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Depends: There are two kinds of mthfr mutations, one can affect homocysteine and the other does not. We do not really know how much an mthfr mutation affects autism, but knowing if there is a mutation means that we know to assist weak methylation processes.
Answered 3/19/2013
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