Would taking zeolite cause an interaction with ssris and nsris amd make them less effective?

I assume you : Are attempting some form of "cleanse". There is no obvious scientific information on benefit for this purpose. I would skip the purification and stay on the meds but if u use it there should ge no interraction. The cleanse is temporary and if you must, take meds, do it 12 hours later but it should not have an effect. You, though, will be the experiment, good luck.

Zeolite ?: The only zeolite i know of that has a medicinal use is found in quickclot, used to stop severe bleeding. That will not interact with an ssri nor nssris.

Not sure, but: I know zeolite is used in detox (ex. Heavy metal/liver detox) with varying degrees of success, due to its binding activity. I doubt any peer-reviewed studies have been conducted on its interaction with ssri's and the like, since it falls into the 'alternative' medicine category. I would space your zeolite and ssri doses as far apart as possible to avoid interactions.