Is luvox (fluvoxamine) really the last choice ssri for depression/ocd because of its many drug interactions?

No: It's one of many drugs ; combos.

Agree with Dr. Bey: Luvox (fluvoxamine) is one of many medication options for the treatment of Obsessive Compulsive Disorder (OCD) and depressive disorders. It's FDA approved indication is Obsessive Compulsive Disorder. It can be a more expensive option than other SSRI's and has only one FDA indication in the US. However it has other approved indications in European countries.