A 49-year-old male asked:
Does luvox (fluvoxamine) have so many side effects and interactions because it is the oldest ssri and as time went on the newer ssri's improved on these problems?
2 doctor answers • 4 doctors weighed in
Psychiatry 42 years experience
Luvox (fluvoxamine): Luvox (fluvoxamine) is not the oldest ssri -- Prozac was the first widely used one, documented in 1974 and fda approved in 1987. Zimelidine came before Prozac -- it was first sold in 1982. However, it was withdrawn from the market due to neurological issues (guillain barre syndrome). Luvox (fluvoxamine) was developed by 1983 and fda approved for use in ocd, in 1994. Side effects are typical for ssri's.
4.7k viewsReviewed >2 years ago
Psychiatry 25 years experience
Interactions: “Fluvoxamine inhibits several cytochrome P450 isoenzymes that are known to be involved in the metabolism of other drugs such as: CYP1A2 (e.g., warfarin, theophylline, propranolol, tizanidine), CYP2C9 (e.g., warfarin), CYP3A4 (e.g., alprazolam), and CYP2C19 (e.g., omeprazole).” REF: https://www.drugs.com/pro/fluvoxamine.html
243 viewsAnswered >2 years ago
Last updated Dec 11, 2018
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