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A 49-year-old male asked:

Does luvox (fluvoxamine) have so many side effects and interactions because it is the oldest ssri and as time went on the newer ssri's improved on these problems?

2 doctor answers4 doctors weighed in
Dr. Pamela Pappas
Psychiatry 43 years experience
Luvox (fluvoxamine): Luvox (fluvoxamine) is not the oldest ssri -- Prozac was the first widely used one, documented in 1974 and fda approved in 1987. Zimelidine came before Prozac -- it was first sold in 1982. However, it was withdrawn from the market due to neurological issues (guillain barre syndrome). Luvox (fluvoxamine) was developed by 1983 and fda approved for use in ocd, in 1994. Side effects are typical for ssri's.
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Dr. Heidi Fowler
Psychiatry 26 years experience
Interactions: Fluvoxamine inhibits several cytochrome P450 isoenzymes that are known to be involved in the metabolism of other drugs such as: CYP1A2 (e.g., warfarin, theophylline, propranolol, tizanidine), CYP2C9 (e.g., warfarin), CYP3A4 (e.g., alprazolam), and CYP2C19 (e.g., omeprazole).” REF: https://www.drugs.com/pro/fluvoxamine.html
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Dec 11, 2018


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