U.S. doctors online nowAsk doctors free
Port Huron, Michigan
A 28-year-old female asked:

How long before i know this cymbalta (duloxetine) is working thoroughly?

2 doctor answers2 doctors weighed in
Dr. Alan Ali
Dr. Alan Alianswered
Psychiatry 33 years experience
Cymbalta (duloxetine): For depression, can take up to 4-6 weeks for full response at optimum dose.
Dr. Robert Olsen
Psychiatry 52 years experience
Up to 6 weeks & more: A problem with antidepressants: there is no sure-fire way to pick one that will work for sure; and no sure fire way to get the correct dosage right off the bat. If you have taken Cymbalta (duloxetine) at a stable dosage for 6 weeks with no change in symptoms, you need either a changed dosage or another or a different medication; increasing dosage is usual next step before switching or adding medications.
Last updated Jun 24, 2014

Disclaimer:

Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.