Port Huron, Michigan
A 28-year-old female asked:
How long before i know this cymbalta (duloxetine) is working thoroughly?
2 doctor answers • 2 doctors weighed in

Dr. Alan Alianswered
Psychiatry 33 years experience
Cymbalta (duloxetine): For depression, can take up to 4-6 weeks for full response at optimum dose.
5.2k viewsAnswered >2 years ago

Dr. Robert Olsenanswered
Psychiatry 52 years experience
Up to 6 weeks & more: A problem with antidepressants: there is no sure-fire way to pick one that will work for sure; and no sure fire way to get the correct dosage right off the bat. If you have taken Cymbalta (duloxetine) at a stable dosage for 6 weeks with no change in symptoms, you need either a changed dosage or another or a different medication; increasing dosage is usual next step before switching or adding medications.
5.2k viewsAnswered >2 years ago
Last updated Jun 24, 2014
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