I have copd, but why am i still short of breath while on oxygen?

Query: Most of the time oxygen can help but certain lung diseases may not respond that well. The main reason you may not see benefit is because of the type of lung disease you have. Other therapies such as inhalers, mucolytics and physical therapy may help more than oxygen. Please provide more details on your condition.

Complicated dyspnea: Shortness of breath relates to the work of breathing as well as oxygenation. COPD when severe enough to need oxygen likely is associated with significant increase in the work of moving air into and out of the lungs. If still short of breath on oxygen there may still low oxygen in the blood stream or the work of getting enough into the blood stream may be causing the shortness of breath.