A member asked:

Is hyaluronidase a safe product to use? is hyaluronidase used to dissolve filler (restylane) under my eyes. i cannot find a lot of information on this drug. has it been around long enough to see if there are any long-term side effects?

7 doctors weighed in across 3 answers
Dr. Dennis Dass answered

Specializes in Plastic Surgery

Your : Your body makes hyaluronidase, and that's why dermal fillers are not permanent. Injecting it to breakdown the Restylane will hasten the dissolution. If you simply have some minor irregularity, sometimes just massaging the area will be sufficient. If you have blueish bumps, you will likely benefit from hyaluronidase.

Answered 3/13/2019

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Dr. Burke Chegar answered

Specializes in Facial Plastic Surgery

YES: Hyaluronidase is a safe. It has been available for several years with an excellent safety profile. It works well in breaking down hyaluronic acid filler quickly within a day or two of injection.

Answered 5/19/2017

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Dr. Thomas Fiala answered

Specializes in Plastic Surgery

Yes: This is a well known drug, with an excellent track record of safety. Occasionally, some people will be allergic to it. It is very useful for dissolving excess filler.

Answered 5/9/2018

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